Effects of sophoroflavonoside and narcissin flavonoids on mitochondrial dysfunction and antioxidant enzyme activity in rat liver poisoned with galoxyfop-r-methyl pesticide

This study delves into the accumulation of residues in liver tissue rats exposed to galoxyfop-R-methyl pesticide. The investigation also evaluates presence malondialdehyde (MDA), a lipid peroxidation (LPO) product, mitochondrial membrane, along with activity antioxidant enzymes catalase, superoxide dismutase (SOD), glutathione reductase (GR), and peroxidase (GP). further explores impact sophoraflavonoloside (SFL) narcissin flavonoids on enzyme over dynamic span 10 40 days. In experimental design, group were subjected pesticide at dosage equivalent LD50/10 through specialized probe. Subsequently, concentration was measured 5th, 10th, 20th, 30th, 40th days post-pesticide exposure. research probes content (MDA) as well enzymes, within context SFL. meticulous examination aids comprehending dynamics responses oxidative stress modulation By investigating intricate interactions between exposure, activity, mechanisms, this contributes broader understanding potential effects counteractive measures concerning pesticide-related challenges biological systems.